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Week 17 Saturday DFS Lineup: Justin Herbert, Derrick Henry, Nico Collins and More

Morgan puts together a DFS lineup for the week 17 Saturday games.

Morgan Rode Dec 26th 11:15 AM EST.

Dec 21, 2025; Baltimore, Maryland, USA;  Baltimore Ravens running back Derrick Henry (22) runs the ball against New England Patriots cornerback Christian Gonzalez (0) during the second half of the game at M&T Bank Stadium. Credit: Mitch Stringer-Imagn Images
Dec 21, 2025; Baltimore, Maryland, USA; Baltimore Ravens running back Derrick Henry (22) runs the ball against New England Patriots cornerback Christian Gonzalez (0) during the second half of the game at M&T Bank Stadium. Credit: Mitch Stringer-Imagn Images

After a three-game NFL slate on Christmas, there's two more games on Saturday before we get to Sunday or Monday. Let's put together a DFS lineup for Saturday's games.

We have to fill nine lineup spots and stay under the $50,000 budget. Let's see what we come up with!

Also be sure to check back for fantasy football breakdowns of all those games as well.

Check out player prop bets, prop bet rankings and public betting splits on FantasySP all season! 

Quarterback - Justin Herbert ($6,000)

I decided on Herbert at the quarterback spot.

He is averaging 19.8 fantasy points per game on the season, and scored 33.2 last week. Herbert has a very tough matchup coming against the Texans, but I believe in him over the other options at QB on Saturday.

Green Bay's starter is in flux, while Tyler Huntley looks likely to start for Baltimore. C.J. Stroud is the other option, and has a very tough test against the Chargers, so I feel like Herbert is the best option for this DFS contest.

Running Back - Omarion Hampton ($6,300)

I added another Charger here with Hampton. 

He is averaging 14.8 fantasy points per game on the season, and tallied 16.5 last week. Hampton has a tougher matchup ahead, but it's more just below average than a truly daunting test.

Hampton could really star as backup Kimani Vidal is at least going to play banged up - if he's out entirely, I think Hampton is a must-start fantasy back in week 17.

Running Back - Derrick Henry ($7,200)

I gave Henry my other RB spot in this DFS lineup.

He is averaging 16.2 fantasy points per game this season, and is coming off a 26.8-point outing last week.

Henry's matchup against the Packers is a very tough one, but with Lamar Jackson at least banged up, I see him being the focal point of the Ravens' offense. It will lead to Henry being a good fantasy option, with volume stats overcoming the tougher matchup.

Wide Receiver - Nico Collins ($7,400)

Collins is my first wide receiver pick.

He is averaging 16.2 fantasy points per game on the season. Collins only scored 9.9 fantasy points last week, but he had 23.5, 19.1 and 21.5 points in three previous contests.

A tougher test against the Chargers awaits, but I think Collins will do enough to finish as a top-three wideout on Saturday. Ideally, he scores at least one touchdown.

Wide Receiver - Zay Flowers ($6,400)

Flowers is my second choice at wide receiver.

He is averaging 14 fantasy points per contest on the season, and is coming off a 22.2-point outing. Flowers has scored 15.8 or more fantasy points in three straight games.

A slightly above-average test against the Packers is what he will face on Saturday. He's a risky starting option with Jackson at least banged up, but as the team's top pass catcher, I think he does enough to post a good fantasy score.

Wide Receiver - Jayden Reed ($3,900)

Reed is among the pass-catching options in Green Bay, and he gets my third wide receiver spot in this lineup.

Reed is averaging 8.1 fantasy points on the season. Since returning from a long absence, he's scored 9.3, 10.5 and 7.1 fantasy points.

A very favorable matchup should help Reed deliver another pretty solid fantasy showing on Saturday. I'm hoping he finishes as the Packers' top pass catcher. That would be helped out by Christian Watson possibly missing the game.

Tight End - Oronde Gadsden ($3,900)

Gadsden is my choice at tight end.

He's averaging 9.1 fantasy points per game on the season. Gadsden scored 1.7 fantasy points last week, and he also scored that amount in week 14. In between, Gadsden scored 10.1 fantasy points.

He has a slightly below-average matchup against the Texans. With the LA receivers facing a tougher test, I'm hoping Gadsden can surprise a bit, and maybe even finish as the team's top pass catcher. If that happens, this DFS lineup could be in great shape to contend for the top score.

Flex - Romeo Doubs ($4,900)

With no real No. 1 wideout in Green Bay, I'm taking a chance on another option here in Doubs.

He's averaging 10.4 fantasy points per game on the season, and is coming off a 19.4-point outing. Doubs was at 5.6 points the week before that, and didn't score at all in week 14, so he's not exactly a super confident pick for me.

In the nice matchup though, I'm hoping he can perform similar to last week. Again, he would be aided by Watson missing the game, but even if he's out there, Doubs could deliver, just like he did in week 16.

DST - Packers DST ($3,200)

There were really good options with every DST playing Saturday, as there's reasons to play them all.

I chose the Packers, who are averaging 5.1 fantasy points per game on the season. They have scored zero and one point over the past two weeks, so that's not exactly great.

A matchup against a hobbled Jackson or Huntley gives me confidence to start the Packers DST though. I think a double-digit fantasy showing is doable, so why not try them.

#dfs #week-17 #start-sit-decision

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