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Thursday Night Football Week 15: Los Angeles Rams @ San Francisco 49ers NFL Best Bets and Top Props

It's time for another Thursday Night Football game and we are once again here to help you cash out.

Mark Morales-Smith Dec 12th 8:37 AM EST.

Dec 8, 2024; Santa Clara, California, USA; San Francisco 49ers wide receiver Jauan Jennings (15) runs with the ball after making a catch in front of Chicago Bears cornerback Kyler Gordon (6) in the fourth quarter at Levi's Stadium. Credit: Cary Edmondson-Imagn Images
Dec 8, 2024; Santa Clara, California, USA; San Francisco 49ers wide receiver Jauan Jennings (15) runs with the ball after making a catch in front of Chicago Bears cornerback Kyler Gordon (6) in the fourth quarter at Levi's Stadium. Credit: Cary Edmondson-Imagn Images

Last week's Thursday Night Football showdown between NFC North rivals the Green Bay Packers and Detroit Lions lived up to the billing and then some. The Lions snuck away with a victory to all but lock up the division. We killed it with our bets, hitting on all three of our best bets and two of our three top props. All year we've been on fire and we look to keep it going this week with another divisional showdown.

This week we get an NFC West battle with the second-place Los Angeles Rams hitting the road to take on the last-place San Francisco 49ers, who are clinging for dear life to their fading playoff hopes. The Niners are down but not out yet, while the Rams have a shot to move into a tie for first place with a win and Seattle Seahawks loss in Week 15. 

NFL Best Bets Week 15

The 49ers season has been marred by injury and the hits kept coming in Week 14 as rookie running back Isaac Guerendo was in the midst of an incredible debut as a starter before suffering a sprained foot. The injury isn't believed to be serious, but could force him to miss this game because of the short week. They would be down to their RB4 Patrick Taylor if the rookie can't go.

The offense is likely to revolve around George Kittle and surprise breakout receiver Jauan Jennings. The Rams' defense has young talent and playmakers, so Brock Purdy could have his work cut out for him in this one.

The Niners' offense also has been a shell of what it usually is this season as well. Injuries and underperformance are both to blame. They will need to step up this week if they are going to hold Puka Nacua, Cooper Kupp, and Kyren Williams in check.

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Matthew Stafford should have a great night if the protection holds up. Although, we wouldn't count on Williams to have a huge game. The 49ers are getting healthier in the front seven and we have seen Blake Corum begin to siphon off some of the workload. Both offenses vs. both defenses are intriguing matchups though.

We are expecting a good game that could go either way. The Rams are young but better than they get credit for and the Niners aren't what they were supposed to be. Both teams have been inconsistent as well so you never quite know what you're going to get. Either way, it should be a ton of fun and we'll help you win some cash. 

The Picks

Spread: Los Angeles Rams +3 (-120)
Over/Under: Over 49 (-108)
Moneyline: San Francisco 49ers (-148)

Player Props of the Night

Prop #1: Patrick Taylor, Any Time TD Scorer (-120)

This is a bet we are making before we get word on Guerendo. So if you're reading this earlier in the day you should throw some money on him to score. If Guerendo is ruled out, which is my expectation, the odds will probably change and make this bet less worthwhile. If Guerendo plays, we would make this bet with even better odds in our favor and hope that Taylor gets more work due to the rookie's ailment. There are a lot of moving parts here, nevertheless, we will roll the dice on Taylor finding the end zone. 

Prop #2: Brock Purdy, Over 4.5 Rushing Attempts (-135)

It's gone mostly unnoticed, but with all the injuries in San Fran, Purdy has been running more. He's rushed the ball at least five times in four of his last six games, totaling 32 attempts during that span. The Rams have a talented young front seven which will force him from the pocket in this game. This is a sneaky good prop that should cover with ease.  

Prop #3: Jauan Jennings, Over 5.5 Receptions (+110)

We absolutely love Jennings to have a monster game in this one. If you exclude that crazy blizzard game in Buffalo, he's been unstoppable over his past four games and he's really been great all year. Even in the blizzard game, he still caught three of five passes for 56 yards in a game that Purdy only threw for a total of 94 yards in.

Nevertheless, in the other four most recent games, he's been targeted 37 times and caught 29 of them. He's topped this mark in all but one of those games and he still caught five passes in that game. With CMC now gone and a void at running back, even more targets should going his way.

As a bonus bet, we also love him to hit his over of 70.5 yards (-120). Again, excluding that blizzard game, he's topped at least 90 receiving yards in three of his last four and he'll clear 100 in this game.  

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