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Deebo Samuel Sr. or James Cook

Who Should I Start? - Week 6 • Start New
Deebo Samuel Sr.

Deebo Samuel Sr.

WR • San Francisco 49ers SF
James Cook

James Cook

RB • Buffalo Bills BUF
OR
EXPERT ANALYSIS

Owners starting Samuel Sr. over Cook

 
 
 
 
START BOTH START BENCH BOTH BN

Samuel Sr. ... 0%

BOTH ... 0%

PROJECTION
FPTS: 0
REC REC YD REC TD FPTS
0 0 0 0
No projection for today.
Coming soon.
Learn More
Outlook Deebo Samuel Sr.

Deebo Samuel Sr. Sidelined Against Washington with Hamstring Injury

Samuel has been officially ruled out for Monday night's matchup against Washington after suffering a hamstring strain in Seattle. Head coach Kyle Shanahan noted the team considered injured reserve, but opted against it with a Week 8 bye looming, pointing to Week 9 as his earliest realistic return.

Fantasy managers must keep Samuel benched this week, where our weekly projection marks him at zero points. While his start rate plummeted to 3%, he remains rostered in 90% of leagues after producing three total touchdowns across five games. Stash him securely and check back often for the latest updates on his recovery.

FantasySP AI Analysis Updated 11 hrs ago
Latest News Deebo Samuel Sr.
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EXPERT ANALYSIS

Owners starting Cook over Samuel Sr.

 
 
 
 
START BOTH START BENCH BOTH BN

Cook ... 88.89%

BOTH ... 0%

PROJECTION
FPTS: 15.68
RUSH ATT RUSH YD RUSH TD REC REC YD REC TD FPTS
20.59 76 0.63 1.58 9 0.02 15.68
No projection for today.
Coming soon.
Learn More
Outlook James Cook

James Cook at Las Vegas — High-Scoring Matchup Keeps RB1 Value Locked In

Lead back James Cook enters Week 6 in Las Vegas commanding the Buffalo backfield ahead of Ray Davis and Ty Johnson, coming off a 25-carry, two-touchdown performance. However, ball security has become an urgent storyline after two fumbles last week prompted head coach Joe Brady to warn that continued miscues will cost him touches.

Even with coach scrutiny, fantasy managers should feel confident slotting him into their lineups across all formats with 100% start rates. Buffalo is favored in a matchup projected to be high scoring, and our weekly projection expects another heavy workload featuring around 21 carries for 94 rushing yards and strong touchdown equity.

FantasySP AI Analysis Updated 11 hrs ago
Latest News James Cook
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Next Up ❱ Performance Comparison
Performance Deebo Samuel Sr.
Fantasy Chart Loading...

REC YDS AVG LONG TD
22110.5140
Season stats based on the past 7 days

REC YDS AVG LONG TD
7476.7141
Season stats based on the past 14 days
Performance James Cook
Fantasy Chart Loading...

ATT YDS AVG TD REC YDS TD
251114.42170
Season stats based on the past 7 days

ATT YDS AVG TD REC YDS TD
371865.033150
Season stats based on the past 14 days
Next Up ❱ Redzone Touches
Redzone Touches Deebo Samuel Sr.
REDZONE
WK OPP ATT TAR REC
1 @LAR 🔓 🔓 🔓
2 MIA 🔓 🔓 🔓
3 ARI 🔓 🔓 🔓
4 DEN 🔓 🔓 🔓
5 @SEA 🔓 🔓 🔓

Redzone data is for premium members only.

Redzone Touches James Cook
REDZONE
WK OPP ATT TAR REC
1 @HOU 🔓 🔓 🔓
2 DET 🔓 🔓 🔓
3 LAC 🔓 🔓 🔓
4 NE 🔓 🔓 🔓
5 @LAR 🔓 🔓 🔓

Redzone data is for premium members only.

Next Up ❱ Own/Start Comparison
OWN/START Deebo Samuel Sr.
OWN
90%
-8.22 compared to last week
START
 
3%
-54.13 compared to last week
OWN/START James Cook
OWN
100%
No change since last week.
START
100%
No change since last week.
Next Up ❱ Consensus Rankings
Expert Consensus Deebo Samuel Sr.
Not Ranked
Average Ranking of Fantasy Experts
Expert Consensus James Cook
5th
Average Ranking of Fantasy Experts
Next Up ❱ Player Breakdowns
Breakdown Deebo Samuel Sr.

    Overview

  • Experts don't even rank him among WR's. Either he is on a bye week or is just plain bad. Based on his stats from the past 30 days, he is currently ranked 20th with 44.40 total points (8.88 avg).
  • Currently 58.06 points behind the leader: Jaxon Smith-Njigba
  • He is listed on the injury report about his Hamstring (Since Oct 11, 2026). Check out his player news for a closer look.
  • Slight decline in numbers lately at 2.1 PPG.

    • Receiving Stats

  • Top 50 in receptions and is currently ranked 46th among WR.
  • Top 75 in targets, though that isn't saying much, and is currently ranked 60th among WR.
  • Top 25 in red zone targets and is currently ranked 25th among WR.
  • Top 6 in red zone receptions and is currently ranked 4th among WR.
  • Top 50 in reception yards with 206 and 12.88 YPC and is currently ranked 45th among WR.
  • Top 20 in Rec TDs with 3 and is currently ranked 16th among WR.

    • Rushing Stats

  • Top 3 in rush attempts with 9 (1.80 per game) and is currently ranked 1st among WR.
  • Top 3 in rush yards with 78 (15.60 per game) and is currently ranked 1st among WR.

    • Bonus Qualities

  • At this point in the season his numbers compared to last years: Receptions: -14, Rec Yards: -94 Rec TDs: EVEN,

    • Season Outlook

  • REC: 65, REC YDS: 715, REC TDS: 7
Breakdown James Cook

    Overview

  • Just about every team utilizies the dreaded 'running backs by comittee' policy. Two solid #1 starters are hard to find.
  • Experts rank this player at 5th among RB's. Based on his stats from the past 30 days, he is currently ranked 6th with 82.30 total points (16.46 avg).
  • Currently 44.4 points behind the leader: Jahmyr Gibbs
  • He is putting up the kind of numbers the experts expected him to.
  • Average points in the past two weeks have increased by 1.6 PPG.

    • Receiving Stats

  • Top 50 in receptions and is currently ranked 42nd among RB.
  • Top 35 in targets and is currently ranked 32nd among RB.
  • Top 50 in Rec TDs with 0 and is currently ranked 43rd among RB.
  • Top 25 in red zone targets and is currently ranked 21st among RB.
  • Top 10 in red zone attempts and is currently ranked 9th among RB.

    • Rushing Stats

  • Top 6 in rush attempts with 95 (19.00 per game) and is currently ranked 6th among RB.
  • Top 3 in rush yards with 532 (106.40 per game) and is currently ranked 3rd among RB.
  • Top 6 in rush tds with 5 (1.00 per game) and is currently ranked 5th among RB.

    • Bonus Qualities

  • At this point in the season his numbers compared to last years: Rush Yards: +82, Rush AVG: +0.6 Rush TDs: EVEN, Receptions: -5, Rec Yards: -58 Rec TDs: EVEN,
  • His touches per game on the ground are great.

    • Season Outlook

  • RUSH ATT: 295, RUSH YDS: 1475, RUSH TDS: 14, REC: 30, REC YDS: 265, REC TDS: 3
Next Up ❱ Health Check
Injury Deebo Samuel Sr.

HAMSTRING - Since Oct 11, 2026

Samuel Sr. has suffered a hamstring strain and is expected to miss multiple weeks.
Injury James Cook

No Injury Reported

Next Up ❱ Matchup Comparison
Matchups Deebo Samuel Sr.

Week 6
San Francisco 49ers VS Washington Commanders

PA/G YDS/G TO INT SACK TDs FSP
29.80364.2073912.73
Compare to same point last season

Overview

  • Experts don"t even rank him among DST's. Either he is on a bye week or is just plain bad. Based on his stats from the past 30 days, he is currently ranked 22nd with 23.00 total points (4.60 avg).
  • Currently 36 points behind the leader: Vikings DST
  • Average points in the past two weeks have remained fairly consistant and rose slightly by 0.9 PPG.

Defensive Stats

  • Top 8 in rush defense with 477 (95.40 per game) and is currently ranked 8th among DST.
  • Ranked 29th in pass defense with 1344 (268.80 per game).
  • One of the worst in points against with 29.80 per game and currently ranked 30th among DST.
  • Top 10 in Total TDs with 1 (0.20 per game) and currently ranked 10th among DST.

Bonus Qualities

  • At this point in the season his numbers compared to last years: Total Yards Against: +157.87, Turnovers: -3 Sacks: -12, INTs: -3, TDs: -1, Points Allowed: +4.58,

Season Outlook

  • SACK: 38, INT: 11, TDS: 5, PA/G: 28.2, YDS/G: 408
Matchups James Cook

Week 6
Buffalo Bills @ Las Vegas Raiders

PA/G YDS/G TO INT SACK TDs FSP
25.80393.801041302.89
Compare to same point last season

Overview

  • Experts don"t even rank him among DST's. Either he is on a bye week or is just plain bad. Based on his stats from the past 30 days, he is currently ranked 11th with 33.00 total points (6.60 avg).
  • Currently 26 points behind the leader: Vikings DST
  • Average points in the past two weeks have dipped quite a bit at 6.6.

Defensive Stats

  • Top 4 in turnovers with 10 (2.00 per game) and is currently ranked 3rd among DST.
  • Ranked 29th in rush defense with 703 (140.60 per game).
  • Ranked 25th in pass defense with 1266 (253.20 per game).
  • Top 10 in sacks with 13 (2.60 per game) and currently ranked 9th among DST.
  • Top 8 in interceptions with 4 (0.80 per game) and currently ranked 8th among DST.
  • One of the worst in points against with 25.80 per game and currently ranked 23rd among DST.
  • Currently ranked 25th in Total TDs with 0 (0.00 per game) among DST.

Bonus Qualities

  • At this point in the season his numbers compared to last years: Total Yards Against: +58.6, Turnovers: +6 Sacks: +5, INTs: +2, TDs: EVEN, Points Allowed: -2,

Season Outlook

  • SACK: 39, INT: 11, TDS: 2, PA/G: 27, YDS/G: 337.7
Next Up ❱ Ratings Comparison
Rating Deebo Samuel Sr.
12.79
FantasySP Player Rating
Rating James Cook
29.31
FantasySP Player Rating
Next Up ❱ Career Comparison
Career Deebo Samuel Sr.
RECEIVING RUSH
YEAR TEAM GP TGTS REC YD AVG TD ATT YD AVG TD
2024 SF 14 81 51 670 13.1 3 42 136 3.2 1
2025 WAS 16 99 72 727 10.1 5 17 75 4.4 1
2026 SF 5 20 16 206 12.9 3 9 78 8.7 0
ON PACE 18 72 58 742 12.9 11 32 281 8.7 0
3-YEAR AVG 10 60 41 466 11.4 3 20 70 3.6 1
Totals 35 200 139 1603 11.5 11 68 289 4.3 2
Career James Cook
RUSH RECEIVING
YEAR TEAM GP ATT YD AVG TD TGTS REC YD AVG TD
2022 BUF 16 91 525 5.8 2 33 21 180 8.6 1
2023 BUF 16 237 1122 4.7 2 54 44 445 10.1 4
2024 BUF 16 207 1009 4.9 16 38 32 258 8.1 2
2025 BUF 16 326 1737 5.3 13 43 36 304 8.4 2
2026 BUF 5 95 532 5.6 5 11 7 31 4.4 0
ON PACE 18 342 1915 5.6 18 40 25 112 4.4 0
3-YEAR AVG 19 286 1427 5 11 50 42 366 8.7 3
Totals 82 1101 5552 5 42 200 158 1337 8.5 9
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Player News

  • Rod Brind'Amour HC • CAR NHL

    Hurricanes Skip Sunday Morning Skate; Brind’Amour to Speak Before Calgary Game

    @CanesPR

  • Scott Arniel HC • WPG NHL

    Jets Coach Arniel Defers Hellebuyck Questions to GM Chevy, Says Team Is Focused on Winning

    @RussoHockey

  • David Bednar RP • NYY MLB

    On The Yankees’ Third Base Dilemma

    MLBTradeRumors

  • J.T. Realmuto C • PHI MLB

    Phillies To Reduce J.T. Realmuto’s Catching Workload

    MLBTradeRumors

  • Carter Verhaeghe C • FLA NHL

    Panthers become 1st team in NHL history with natural hat tricks in 3 straight games

    Pierre Lebrun

  • Freddy Peralta SP • TB MLB

    Freddy Peralta Enters in Relief to Protect 2–1 Lead After Martinez Exits

    @TBTimes_Rays

  • Bo Nix QB • DEN

    Aqib Talib Criticizes Ryan Fitzpatrick Over Bo Nix Comments

    @ProFootballTalk

  • Kyle Juszczyk FB • SF

    Juszczyk Set to Return for 49ers; Evans Questionable for Buccaneers

    @ProFootballTalk

  • Zach Wilson QB • NO

    Drew Mestemaker Recreates Zach Wilson’s Famous Pro Day Throw in a Live Game

    @Ben_Baby

  • Kyle Juszczyk FB • SF

    Kyle Juszczyk set to return for 49ers, Mike Evans listed as questionable

    profootballtalk.com

  • Evan McPherson K • CIN

    After overcoming severe colitis in 2024, Auburn's Alex McPherson kicks game-winner vs. No. 1 Georgia

    profootballtalk.com

  • Evan McPherson K • CIN

    Auburn Kicker Alex McPherson Overcomes Severe Colitis to Beat No. 1 Georgia with Game-Winning Field Goal

    @ProFootballTalk

  • David Bednar RP • NYY

    On The Yankees’ Third Base Dilemma

    MLBTradeRumors

  • J.T. Realmuto C • PHI

    Phillies To Reduce J.T. Realmuto’s Catching Workload

    MLBTradeRumors

  • Freddy Peralta SP • TB

    Freddy Peralta Enters in Relief to Protect 2–1 Lead After Martinez Exits

    @TBTimes_Rays

  • Jefferson Rojas SS • NYM

    Mets Prospect Jefferson Rojas Hits Two Home Runs in Dominican Winter League Game

    @MLBPipeline

  • Junior Caminero 3B • TB

    Junior Caminero’s 110-MPH Double Gives Rays a 2–1 Lead

    @JeffPassan

  • Patrick Forbes P • ARI

    Diamondbacks Prospect Patrick Forbes Adds Sweeper to His Pitching Arsenal

    @MLBPipeline

  • Naji Marshall SF • DAL

    Mavericks Highlight Naji Marshall in “The Blueprint” Feature

    @dallasmavs

  • LeBron James SF • PHI

    LeBron James Set to Begin Record-Breaking 24th NBA Season Against the Knicks

    @NBA

  • Alondes Williams PG • WAS

    Wizards Waive Trevor Keels, Chris Livingston and Alondes Williams

    @IraHeatBeat

  • Nikola Jokic C • DEN

    Nikola Jokić’s Preseason Dime Sets the Stage for an MVP Showdown With Shai Gilgeous-Alexander on ESPN

    @NBA

  • Devin Carter PG • BOS

    Celtics reportedly converting this former Providence College standout to two-way contract

    Boston Globe

  • Darius Garland PG • LAC

    Darius Garland Joins LA Clippers’ Feed the Community Event

    @LawMurrayTheNU

  • Rod Brind'Amour HC • CAR

    Hurricanes Skip Sunday Morning Skate; Brind’Amour to Speak Before Calgary Game

    @CanesPR

  • Scott Arniel HC • WPG

    Jets Coach Arniel Defers Hellebuyck Questions to GM Chevy, Says Team Is Focused on Winning

    @RussoHockey

  • Carter Verhaeghe C • FLA

    Panthers become 1st team in NHL history with natural hat tricks in 3 straight games

    Pierre Lebrun

  • Jake Oettinger G • DAL

    Jake Oettinger Dominates His First Six Starts with a .952 Save Percentage and Three Shutouts

    @JesseGranger_

  • Dylan Garand G • NYR

    Kent Johnson’s OT Winner Lifts Columbus Past Rangers, 1-0

    @Peter_Baugh

  • Sergei Bobrovsky G • TOR

    Bobrovsky Allows 3+ Goals in Each of His First Six Games, Echoing a Leafs Record from 2009

    @JeffVeillette

Matchups

Week 6
ARI @LAR
ATL vs CHI
BAL @CLE
BUF @LV
CAR @PHI
CIN vs BYE
DAL @GB
DEN vs SEA
DET vs BYE
HOU @JAC
IND vs TEN
KC vs LAC
MIA vs BYE
MIN vs BYE
NE vs NYJ
NO @NYG
PIT @TB
SF vs WAS
Matchup Time Pitchers
CLE vs TB 08:00 EDT EST
Matchup Time
No games scheduled
Matchup Time
BOS @LA 9:00 PM EST
BUF @MON 7:00 PM EST
CAR @WPG 3:30 PM EST
CBJ vs NYR 7:00 PM EST
CHI vs DAL 7:00 PM EST
DET vs SJ 7:00 PM EST
EDM @UTA 10:00 PM EST
FLA vs SEA 6:00 PM EST
NJ @WAS 1:00 PM EST
NSH vs STL 8:00 PM EST
NYI @TOR 7:00 PM EST
OTT @PHI 7:00 PM EST
PIT @VGK 10:00 PM EST
TB vs VAN 4:00 PM EST