What a graphic from the NFL Network broadcast. Jonathan Taylor is unstoppable. pic.twitter.com/lmHztUohOt

Carson Wentz vs the #Cardinals: 🔹 18-28 🔹 225 yards 🔹 2 TDs 🔹 113.0 passer rating 🔹 W pic.twitter.com/5caDHAh3Xj

The #Colts beat the #Cardinals in Arizona despite not having Darius Leonard, Quenton Nelson, Ryan Kelly and Mark Glowinski, plus Eric Fisher and Jack Doyle getting hurt in game. Arizona has lost three in a row.

And now, hours before their game against the Cardinals, the Colts have placed LB Darius Leonard, S Khari Willis and WR Zach Pascal on the Reserve/Covid19 list. They're out tonight.

One of the game balls the Colts gave out tonight: GM Chris Ballard. "When you win a game like this, you thank the man that put the roster together," said Frank Reich.

Jim Irsay: "This (win) makes you think … what can't we do?"

Frank Reich and Matt Eberflus had themselves a night.

Wentz delivers a gift to T.Y. Hilton for SIX! #ForTheShoe 📺: #INDvsAZ on @NFLNetwork 📱: bit.ly/3H8gKOD pic.twitter.com/6UH2YGVGxX

Man, George Odum has had a really, really good game. On a night where your depth has been tested like no other, he might top the list of guys who have risen to the occasion.

When it rains, it pours: Chris Reed now hurt. Will Fries is in. If someone else goes down on the line, they might have to give Anthony Castonzo a call at halftime.

It'll be four backup O linemen the rest of the way for the Colts. Eric Fisher ruled out with a knee injury. Whoo boy.

Touchdown to T.Y. Hilton. Play was designed to go to Nyheim Hines, it looked like, Wentz didn't like what he saw and found Hilton wide open crossing.

Michael Pittman has to clean up some of this messiness in his game. He's playing great this year but too many penalties.

I will say this for Ashton Dulin: He comes through practically every time he's asked. I want to see more.

Feel like the Colts will need a huge play from DeForest Buckner or Kenny Moore to win this one.

Losing Jack Doyle really changed the way we called the game. "He's one of our top blockers." Reich pic.twitter.com/nQRLe2Krrt

Michael Strachan the only notable inactive tonight for the Colts, who'll have Keke Coutee up instead of him at WR.

With Eric Fisher limping to the Colts' locker room, the team now has one starting offensive lineman left in the game: Braden Smith.

Danny Pinter should at least get credit for five rushing yards there.

That's 7 points left on the field by the Cardinals placekicking unit. Loved the 3rd down wrinkle of E.J. Speed showing blitz, reverting back to zone.

Very sound rush there on 3rd down by Indy. Dayo Odeyingbo with the stunt leading to a throwaway. Important 3-and-out.

What a time for Dezmon Patmon's first career TD. Wentz was outstanding on that drive. #Colts

Seahawks activated DE Kerry Hyder off COVID list today but placed CB Bless Austin on it. Seattle also activated 5 players off practice squad: DT Myles Adams, S Josh Jones, TE Tyler Mabry, LB Edmond Robinson and WR Cody Thompson.

#Colts literally will run out of offensive linemen soon. I believe rookie Will Fries and practice squad call-up Carter O'Donnell are all that's left on the bench.

Kwity Paye's speed has been impressive chasing Murray a couple of times.

Keep in mind, unvaxxed players miss at least 10 days. So that's 2 games. Including Quenton Nelson. twitter.com/mchappell51/st…

I think the Colts are down to practice squad call-up Carter O'Donnell as the last offensive lineman left on the bench.

The Indianapolis Colts have suffered another loss on the offensive line as they get ready to take on the Arizona Cardinals on Christmas Day. Already without starting center Ryan Kelly and starting right guard Mark Glowinski, they will now be without All-Pro starting left guard Quenton Nelson.

Nelson was placed on the COVID list Friday. Earlier in the week, he missed some practice with an illness.

Kelly is out for personal reasons, as his family mourns the death of their unborn daughter. Glowinski was added to the COVID list Thursday. With Nelson now out as well, it means the Colts will play without their entire starting interior offensive line

We are almost to point where Colts need to know who on their defense played OL in high school I was looking thru DeForest Buckner's maxpreps profile to see ... This is the sort of thing that cannot happen w/o something extraordinary like the sudden covid designations

Honestly, that's a remarkable play by T.J. Carrie. Trick punt return by the Cardinals. Punt returner acts like the ball is headed in the opposite direction, they run a guy who looks like he's blocking back to catch the punt.