NFL Matchups 2021 Week 16

Final O/U: 45.5
49ers
10-7-0
17
Titans  +3.5
12-5-0
20
12/23 08:20 PM | Nissan Stadium
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Final O/U: 46.5
Browns
8-9-0
22
Packers  -7.5
13-4-0
24
12/25 04:30 PM | Lambeau Field
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Final O/U: 48
Colts
9-8-0
22
Cardinals  -3
11-6-0
16
12/25 08:15 PM | State Farm Stadium
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Final O/U: 42.5
Lions
3-13-1
16
Falcons  -7.5
7-10-0
20
12/26 01:00 PM | Mercedes-Benz Stadium
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Final O/U: 44
Buccaneers
13-4-0
32
Panthers  +10.5
5-12-0
6
12/26 01:00 PM | Bank of America Stadium
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Final O/U: 43
Ravens
8-9-0
21
Bengals  -7.5
10-7-0
41
12/26 01:00 PM | Paycor Stadium
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Final O/U: 45.5
Chargers
9-8-0
29
Texans  +12.5
4-13-0
41
12/26 01:00 PM | NRG Stadium
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Final O/U: 48.5
Rams
12-5-0
30
Vikings  +3
8-9-0
23
12/26 01:00 PM | U.S. Bank Stadium
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Final O/U: 43.5
Bills
11-6-0
33
Patriots  -1
10-7-0
21
12/26 01:00 PM | Gillette Stadium
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Final O/U: 42.5
Jaguars
3-14-0
21
Jets  -2.5
4-13-0
26
12/26 01:00 PM | MetLife Stadium
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Final O/U: 41
Giants
4-13-0
10
Eagles  -11
9-8-0
34
12/26 01:00 PM | Lincoln Financial Field
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Final O/U: 41
Bears
6-11-0
25
Seahawks  -7
7-10-0
24
12/26 04:05 PM | Lumen Field
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Final O/U: 44.5
Steelers
9-7-1
10
Chiefs  -10.5
12-5-0
36
12/26 04:25 PM | Arrowhead Stadium
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Final O/U: 42
Broncos
7-10-0
13
Raiders  +1
10-7-0
17
12/26 04:25 PM | Allegiant Stadium
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Final O/U: 46
Commanders
7-10-0
14
Cowboys  -9.5
12-5-0
56
12/26 08:20 PM | AT&T Stadium
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Final O/U: 37.5
Dolphins
9-8-0
20
Saints  +3
9-8-0
3
12/27 08:15 PM | Caesars Superdome
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