Really good idea by Sean McDermott and Brian Daboll to give Matt Breida a bigger role tonight. This is what we've been talking about since the summer. Make the two best backs earn the playing time and go with them on game day.

This route by Stefon Diggs was just ridiculous 🔥 pic.twitter.com/50LzH39Jwu

Happy Thanksgiving everyone. Hoping it's been a great day. Looking forward to my man Josh Allen (and the Bills) to take it to the Saints. Should be a beat down. See you tomorrow live from The Match

#Bills star CB Tre'Davious White (knee) was downgraded to out, per the broadcast. A significant loss.

#Bills RB Zack Moss is expected to be a healthy scratch tonight against the #Saints, per source. Moss leads the team with 4 rushing TDs despite dwindling snaps in recent weeks. But with the offense scuffling, they'll shake it up and go with Devin Singletary and Matt Breida.

The Saints fans just booed the hell out of Matt Haack, Tyler Bass and Reid Ferguson.

Dawson Knox finds the end zone for the second time tonight and seventh time this season. That sets a new franchise record for receiving TDs in a season a Bills tight end.

Expected to be healthy scratch in favor of Singletary, Breida

Bills RB Zack Moss is expected to be a healthy scratch tonight against the #Saints, per source.Moss leads the team with 4 rushing TDs despite dwindling snaps in recent weeks. But with the offense scuffling, they’ll shake it up and go with Devin Singletary and Matt Breida. (NFL Network - Tom Pelissero)

FF Today's Take: This doesn't come as a total surprise after a report from New York Upstate's Ryan Talbot suggested that Thursday's game could be a "Matt Breida game." Buffalo's backfield has been a mess for most of the season, but Breida could be given a chance to take the lead role with another strong effort tonight. Singletary and Breida should remain on fantasy benches in most leagues, but Moss being inactive could mean Josh Allen is an even better bet to score a rushing touchdown.

Ed Oliver said he bought so many tickets for friends and family for the game today he basically played for free 🤣

We've activated WR Marquez Stevenson from the Injured Reserve list DT Eli Ankou and DT Brandin Bryant have been elevated from the practice squad for tonight's game. #BillsMafia pic.twitter.com/KjfNY32oR6

Micah Hyde says Isaiah McKenzie is a pro and handled getting benched selflessly. Said he was cheering everyone in on the sidelines throughout the game. Micah added a lot of guys are in his ears letting him know what he means to team.

Trevor Siemian, Bradley Roby and Emmanuel Sanders playing a game in the Superdome. I feel like I stepped out of the DeLorean in New Orleans, circa November 2016, when the Broncos last visited there.

Jordan Poyer says Ed Oliver is a stud and comes to work every day with high energy and a high motor.

Isaiah McKenzie is a healthy scratch. He's not injured. It's strictly a numbers game. Kumerow likely gets nod over him because of ability to block.

It's so weird how just about every broadcast team highlights Tremaine Edmunds.

Dion Dawkins gives up the sack on 3rd and long. Bills have to punt. Not enough variety and not even Diggs.

Ryan Bates is in at RG for Cody Ford.

Mario Addison records is team-leading 4th sack of the season on 3rd and short. Eli Ankou and Brandin Bryant were in on the play and generated some pressure on the rush. Bills got it back up 7-0 w/ 3:21 left in 1st quarter.

Gabriel Davis with a nice catch and impressive tight rope walking near the sidelines to get some extra yards. Ends up going for 21.

Tre'Davious White has been downgraded to out (knee). Dane Jackson will go the rest of the way in his spot. #Bills

4. Because he's been the least effective pass rusher off the edge on the roster. He has a lower pressure rate than Star Lotulelei. twitter.com/vstathop/statu…

Punting was the right choice there. Matt Haack with a nice punt that is downed at the 12 yard line.

Eli Ankou and Brandin Bryant are active after getting the call up from the practice squad. Bills are determined to stop the run today. Ankou is 325.

Nice block by Mitch Morse on the inside on that screen for a TD. Did a good job sustaining his block to leave Breida a crease when he cut it back inside to reach the end zone. It's a runaway in the Big Easy. 31-6 #Bills

Sean McDermott starts his press conference by wishing everyone a happy Thanksgiving and then specifically notes the performance of the kickoff coverage.

Update (10:01 p.m.): White has be downgraded to out by the Bills:

Tre’Davious White has been downgraded to out (knee). https://t.co/02kqLlblnV

— Buffalo Bills PR (@BuffaloBillsPR) November 26, 2021

The Buffalo Bills went down one player on each side of the ball within minutes of each other against the New Orleans Saints (5-5).

The first came from the Bills (6-4) offense. Offensive lineman Cody Ford went down with an arm issue and he is questionable to return