"Jimmy Garoppolo isn't good enough to take us where we want to go." "What should we do?" "We should get rid of him." "How?" "Let's draft a guy who will be ready in 2-3 years and keep Jimmy until then."

5 carries, 57 yards and a TD. All Elijah Mitchell on the opening drive. #FTTB @EliMitch15 📺: #INDvsSF on NBC 📱: bit.ly/3Cb5cb6 pic.twitter.com/FEx1NlHRyM

Brandon Aiyuk kicked that ball straight through a loophole in the rulebook

Kyle Shanahan has a tremendous reputation. I just realized he has one winning season as a head coach pic.twitter.com/SXoRQ3nG8U

That 56-yard FG by Joey Slye was longest for #49ers since Phil Dawson hit 56-yarder vs Cardinals 12/29/13

Ballgame. Dre Kirkpatrick had an opportunity to make a play and never even challenged it.

Another deep pass, another #49ers pass interference. This one is on Jaquiski Tartt. And that makes it 13 PI penalties on the season for 212 + 38 = 250 yards.

Ross Dwelley ready and willing to usher in #NFL National Tight End Day as stunt double for #49ers George Kittle mercurynews.com/2021/10/24/49e…

Third down. Xavier Rhodes breaks up Jimmy Garoppolo's pass for Deebo Samuel. He stepped out of bounds. No pick six.

Nick Bosa continues winning essentially every pass rush and Fred Warner did a great job holding his ground in space there

Dre Kirkpatrick -- filling in for Emmanuel Moseley -- was in a great spot for that pick, but, well, you might not want him in the low post in your next pickup basketball game.

Nick Bosa rushed from an outside linebacker alignment on that 3rd down. He and Dee Ford teamed up for the pressure that should've been a Moseley INT. The 49ers are dominating in pass-rush situations up front. They just need a little help from their DBs

Activated #49ers uniform numbers: 7-QB Nate Sudfeld 23-RB JaMycal Hasty 53-LB Tyrell Adams 84-TE Tanner Hudson twitter.com/nbcs49ers/stat…

First game active for 49ers' second-round pick Aaron Banks pic.twitter.com/A4r6Je2MIP

And Josh Norman completely sold out on that Indy fake for the TD. Rough drive for Norman after he forced that fumble

#49ers inactives for tonight's game vs. Colts: QB Trey Lance WR Travis Benjamin CB Ambry Thomas CB Deommodore Lenoir OL Trent Williams DL Javon Kinlaw DL Maurice Hurst

I'll have to see that again, I thought Ross Dwelley let go and did not hold.

Deommodore Lenoir is also inactive. All five 49ers linebackers including Tyrell Adams are active. SF obviously loading up the front 7 as much as possible for the rain game against an Indy team that runs well. Similar thought process on offensive end with Travis Benjamin inactive twitter.com/49ers/status/1…

LB Marcell Harris was last out of the locker room for warm-ups. He's got a full cast/club on his right hand to protect his injured thumb. #captcaveman

WR Jauan Jennings is active this week. This is shaping up to be a mudder game, after all. twitter.com/mattbarrows/st…

Smartest third-down strategy when facing 49ers defense: play for the pass-interference penalty K'Waun Williams draws 40-yarder PI penalty on third-and-10 underthrow

This seems like it's already been Charlie Woerner's busiest game. #TEday

The 49ers on Sunday officially ruled out left tackle Trent Williams before their Sunday night showdown against the Indianapolis Colts. He was listed among the team’s inactives after officially being listed as ‘doubtful.’

Here’s who won’t suit up for the 49ers:

LT Trent Williams (ankle)DT Javon Kinlaw (knee)DT Maurice Hurst (calf)QB Trey Lance (knee)WR Travis BenjaminCB Deommodre LenoirCB Ambry Thomas

Rookie offensive tackle Jaylon Moore will start in Williams’ place. Moore played 22 snaps in Week 4 when Williams left with a shoulder injury. He also played a lot of left tackle in the preseason after spending his four-year career at Western Michigan occupying that spot on the offensive line

With Maurice Hurst (calf) and Javon Kinlaw (knee) inactive, Kentavius Street likely will see a lot of action, especially if the Colts go heavy on the ground as expected.

Arden Key was in at DT on that last snap.